Last Updated: July 08, 2020
Celia Miller Author: Celia Miller

Best Glucosamine for Dogs

Best Glucosamine for Dogs

After over 100 hours of testing, our pet experts are comfortable recommending Turmeripure Lab Grade Glucosamine Chondroitin for your senior dog’s joint pain. Research shows that giving your dog glucosamine supplements can help rebuild cartilage, alleviating arthritis and increasing mobility. Dogs age faster than humans and even though it’s hard to see our beloved pups get older, there are things we can do to help. The supplements by Turmeripure use some of the best, natural ingredients that are proven to improve your dog’s quality of life.

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Best Quality
Turmeripure Lab Grade Glucosamine Chondroitin
Turmeripure Lab Grade Glucosamine Chondroitin Best Quality
$0
Review manufacturer turmeripure
on turmeripure
10/10
  • What we Like
  • Hemp oil
  • FDA approved manufacturing
  • Appealing flavor
  • What we Dislike
  • Higher price point
Product Details
SUPPLEMENT TYPE: Chewables
DOSAGE SIZE: 520 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

This is a premium product containing high percentages of many great ingredients such as turmeric (curcumin), green lipped mussels (anti-inflammatory), yucca (anti-arthritic), omega 3 fatty acids, MSM, and hemp oil, which is proven to help alleviate pain and discomfort. The chicken flavoring makes these supplements palatable to dogs and easier to feed. It is a higher price point but contains premium ingredients and BioPerine® which is a patented black pepper extract designed to increase the bioavailability of the ingredients in this product making them easier to absorb and be utilized by your dog.

Nutramax Dasuquin
Nutramax Dasuquin
$51
Review manufacturer amazon
on amazon
8/10
  • What we Like
  • Contains ASU to manage pain levels
  • Contains MSM
  • Pork liver flavored
  • What we Dislike
  • Higher price point
  • Harder chews
Product Details
SUPPLEMENT TYPE: Hard Chewable
DOSAGE SIZE: 600 MG Glucosamine
DOG SIZE: Small
Medium
or Large
SOURCE: Made in USA
Our Review

Dasuquin is the follow-up supplement to Cosquin made by Nutramax. Both of these products contain glucosamine and chondroitin. Dasuquin includes an additional compound ASU (Avocado/Soybean Unsaponifiables), another ingredient to protect the cartilage matrix and support joint function and enhance the effects of the glucosamine and chondroitin. Dasuquin also comes in soft chews and Advanced formula that’s prescription only. Easily one of the most widely used products on the market, Nutramax products are manufactured in the US to pharmaceutical grade standards.

Best Budget
Nutramax Cosequin DS Plus with MSM Chewable Tablets
Nutramax Cosequin DS Plus with MSM Chewable Tablets Best Budget
$0
Review manufacturer chewy
on chewy
9/10
  • What we Like
  • Bioavailable (smaller) molecules for better absorption
  • Manganese ascorbate added to optimize healing
  • Appealing flavor
  • What we Dislike
  • Counterfeit products sometimes sold on Amazon
Product Details
SUPPLEMENT TYPE: Hard Chewables
DOSAGE SIZE: 600 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in USA
Our Review

Cosequin has set a high standard for joint supplements for many years and while Dasuquin is often touted as the more advanced of the two, some dogs do better with Cosequin. It is simply formulated, tasty and can be crushed if your dog will not take them easily. It is in a more affordable price bracket and comes in hard or soft chewable form. Because this is such a widely available product both online and in stores, it is often counterfeited so we recommend purchasing through Chewy or another distributor that does not carry third-party products.

Phycox MAX Soft Chews Joint Support Dog Supplement
Phycox MAX Soft Chews Joint Support Dog Supplement
$0
Review manufacturer chewy
on chewy
8/10
  • What we Like
  • Lots of other good ingredients
  • Anti-inflammatory additives
  • Grain-free
  • What we Dislike
  • Larger chews may need to be cut up
  • Strong odor
  • May aggravate allergies in dogs
Product Details
SUPPLEMENT TYPE: Soft Chewable
DOSAGE SIZE: 500 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

This is an outstanding supplement full of lots of other great ingredients such as cranberry extract, flaxseed oil, and turmeric. Unfortunately some dogs who are extremely sensitive may have a bad reaction but Phycox makes a hypoallergenic version of this supplement. The chews are large and may be difficult to cut in half for smaller dogs.

Activphy 75 Count Patented Joint Support Regular Soft Chews
Activphy 75 Count Patented Joint Support Regular Soft Chews
$40
Review manufacturer amazon
on amazon
7/10
  • What we Like
  • Additional helpful ingredients
  • Soft chew
  • Appealing flavor
  • What we Dislike
  • Quality control/reseller issues
Product Details
SUPPLEMENT TYPE: Soft Chewable
DOSAGE SIZE: 500 mg glucosamine
DOG SIZE: Small
Medium/Large
SOURCE: Made in the USA
Our Review

These are formulated to be similar to Phycox with the addition of blue-green algae extract and 500 mg of glucosamine. It’s guaranteed to be palatable to your dog and the chews are soft and easy to cut in half if needed. ActivPhy is a relatively new brand manufactured in the US by H&C Animal Health.
We were concerned about some quality control issues shown on Amazon with differing appearances between different containers of the same product but the manufacturer is US-based and buying directly from Amazon and not resellers should ensure you get an authentic product.

VetriScience Laboratories GlycoFlex Plus Hip and Joint Supplement
VetriScience Laboratories GlycoFlex Plus Hip and Joint Supplement
$0
Review manufacturer amazon
on amazon
9/10
  • What we Like
  • High glucosamine content
  • Duck-flavored chew
  • What we Dislike
  • Chewables may be too hard for some dogs
  • Strong odor
Product Details
SUPPLEMENT TYPE: Chewable formula
DOSAGE SIZE: 1000 mg
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

This is an outstanding supplement that checks all the boxes with lots of great ingredients and with 1000 mg, one of the highest amounts of glucosamine available in chewable supplements on the market. Unfortunately it can upset a dog’s stomach if not he’s not eased carefully into the dosage so if your dog has a sensitive stomach you may want to start with Glycoflex Everyday or Sport.

Bayer Synovi G4 Soft chews for Dogs, Joint Supplement
Bayer Synovi G4 Soft chews for Dogs, Joint Supplement
$0
Review manufacturer chewy
on chewy
7/10
  • What we Like
  • Soft chew format
  • Palatable flavor
  • Additional beneficial ingredients
  • What we Dislike
  • Chews are large
Product Details
SUPPLEMENT TYPE: Soft Chewable
DOSAGE SIZE: 450 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

This is an outstanding soft-chew with a great blend of ingredients and vitamins including creatine to enhance muscle recovery and health. We had to detract points because it contains grain and sugar, both which could be detrimental to dogs who may have dietary requirements or are diabetic. While this may make it more palatable to picky dogs it may be a dealbreaker for some pet owners.

Extend Joint Care Natural Glucosamine
Extend Joint Care Natural Glucosamine
$0
Review manufacturer chewy
on chewy
6/10
  • What we Like
  • Rich beef flavor
  • Chicken collagen
  • Easy to mix with water
  • What we Dislike
  • Higher price point
  • Larger dogs will need more than one packet/day
  • May irritate dogs' digestion
Product Details
SUPPLEMENT TYPE: Powder style
DOSAGE SIZE: 300mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in USA
Our Review

This is powdered supplement that comes in easy to dispense packets. It’s fairly expensive and due to the dosage you may need to feed a larger dog more than one packet per day in the beginning of his treatment regimen. We like how tasty it is to dogs but it can upset their stomachs easily particularly if they have food allergies. It contains oat flour. The price point is why we’re subtracting points. We don’t recommend buying it on Amazon as quality control issues and price fluctuations with resellers cause issues.

Pet Health Solutions Joint MAX Triple Strength Soft Chews
Pet Health Solutions Joint MAX Triple Strength Soft Chews
$0
Review manufacturer chewy
on chewy
6/10
  • What we Like
  • Antioxidants
  • Creatine
  • What we Dislike
  • Not very soft
  • Some dogs don't like the taste
Product Details
SUPPLEMENT TYPE: Soft chewable
DOSAGE SIZE: 1000 mg
DOG SIZE: medium
large
SOURCE: Made in USA
Our Review

These contain a full 1000mg of glucosamine and other great ingredients including creatine, vitamins, ALA acid, hyaluronic acid and an antioxidant blend. That’s why we were disappointed to see that molasses was also included and that contains sugar so diabetic dogs should not use this product. The ingredients specify “non bovine liver” and so if your dog is allergic to poultry the liver powder used in this product is chicken-based and may also cause a problem. These chews may not be as soft as some and may crumble if they dry out.

Joint Care Extra Strength Soft Chews for Dogs by Drs. Foster & Smith
Joint Care Extra Strength Soft Chews for Dogs by Drs. Foster & Smith
$0
Review manufacturer petco
on petco
7/10
  • What we Like
  • Good dosage of glucosamine
  • Smaller chews
  • What we Dislike
  • Contains dairy
  • Higher price point
Product Details
SUPPLEMENT TYPE: Soft chewables
DOSAGE SIZE: 1000 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Unspecified
Our Review

These chews have a great range of ingredients but are not grain or dairy free so dogs with sensitive tummies beware. We do like the higher dosage of turmeric and hyaluronic acid. They are not exactly a soft chew so some dogs may struggle with the density and texture of these. They can only be ordered through the Drs. Foster and Smith website and can be very expensive even with free shipping.

NaturVet ArthriSoothe Gold Level 3 Dog & Cat Soft Chews
NaturVet ArthriSoothe Gold Level 3 Dog & Cat Soft Chews
$0
Review manufacturer chewy
on chewy
7/10
  • What we Like
  • Grain free
  • No sweeteners
  • What we Dislike
  • Not as appealing to some dogs
  • Not very soft
Product Details
SUPPLEMENT TYPE: Soft chewables
DOSAGE SIZE: 500 mg glucosamine
DOG SIZE: small
medium large
SOURCE: Made in USA
Our Review

This is a great blend for dogs who are already experiencing pain and inflammation with an enzyme blend, hyaluronic acid to support the synovial fluids around the joints and vitamins. It may be a little more difficult for older dogs to chew. The taste is not as appealing to many dogs. We like that NaturVet offers 3 levels of glucosamine supplements for dogs in various life stages so be sure to look at the other 2 if you aren’t sure this one will work for your pet.

Best Liquid Supplement
Liquid Health Pets Original K9 Glucosamine Dog Supplement
Liquid Health Pets Original K9 Glucosamine Dog Supplement Best Liquid Supplement
$0
Review manufacturer chewy
on chewy
9/10
  • What we Like
  • Easy to dose
  • Hyaluronic acid (10mg)
  • Allergen free
  • What we Dislike
  • Shorter shelf life
  • May not be as appealling to some dogs
Product Details
SUPPLEMENT TYPE: Liquid style
DOSAGE SIZE: 1600 mg glucosamine (per fl oz)
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

This is a great product that makes it easy to administer dosage according to the weight of your dog without breaking up chews or pills. It contains high levels of all the right ingredients including glucosamine, MSM, manganese, and the highest quantity of hyaluronic acid in a supplement we’ve seen. We love that it’s free of most allergens that irritate a dog’s digestive system and also includes aloe vera gel- another great ingredient. It is sweetened with stevia which may make it more attractive to dogs who are picky about taking medicine or supplements without the complications added sugar can cause. It may still not be as palatable to some dogs as chews or products containing meat byproducts or flavoring. It’s still an extremely versatile product that makes giving your dog glucosamine in his diet easy and convenient.

Best Powdered Supplement
K9 POWER Joint Strong Joint Health & Mobility Dog Supplement
K9 POWER Joint Strong Joint Health & Mobility Dog Supplement Best Powdered Supplement
$0
Review manufacturer chewy
on chewy
9/10
  • What we Like
  • Easy to dose
  • Appealing flavor
  • Anti-oxidant blend
  • What we Dislike
  • May not be suitable for dogs with allergies
  • Contains dairy and grain
Product Details
SUPPLEMENT TYPE: Powder style
DOSAGE SIZE: 1150 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Made in the USA
Our Review

As long as your dog does not have allergies this is a well-rounded blend containing high levels of hyaluronic acid, turmeric, collagen, anti-oxidants, hyaluronic acid, and superfoods like kelp and berries to help with addressing inflammation in the body. It’s thoughtfully blended and more appealing to dogs taste-wise than other powders and even some chews. We especially like that you can buy it in 1 lb, 2 lb, 4 lb or 8 lb jars so you can try it out first without investing in a giant bucket of it.

G-MAX JOINT SUPPORT
G-MAX JOINT SUPPORT
$0
Review manufacturer pawlabs
on pawlabs
2/10
  • What we Like
  • High amount of turmeric
  • What we Dislike
  • High pricepoint
  • Little to no documentation on sourcing or company
Product Details
SUPPLEMENT TYPE: Pill style
DOSAGE SIZE: 250 mg glucosamine
DOG SIZE: small
medium
large
SOURCE: Unspecified
Our Review

This product is featured on a flashy website but we were unable to obtain any documentation on the company or where the ingredients are sourced from. It appears to be a product drop-shipped as the company address differs from the on-demand fulfillment company address listed for returns. This product does contain a nice portion of turmeric but there are fillers like silicone in it and again, not knowing if these were made in the USA or in China is enough to make us hesitate to feed these pills to our dogs.

Best Products Best Glucosamine for Dogs
Product Name Best for Rate
Turmeripure Lab Grade Glucosamine Chondroitin Best Quality 10
Nutramax Cosequin DS Plus with MSM Chewable Tablets Best Budget 9
Liquid Health Pets Original K9 Glucosamine Dog Supplement Best Liquid Supplement 9
K9 POWER Joint Strong Joint Health & Mobility Dog Supplement Best Powdered Supplement 9

How to Choose A Glucosamine Supplement

Your dog’s joint bones are cushioned by cartilage, which is strong connective tissue that keeps the bones from rubbing or rubbing together. It is the cushiony area that absorbs impact when bones and joints are moved. When this cartilage wears thin or is damaged, it is extremely painful when the bones rub together during movement and too much of this bone-on-bone contact can cause bone erosion and extremely painful outgrowths to form. Healthy cartilage allows your dog a full range of movement and flexibility.

Cartilage contains cells called chondrocytes, which produce the “matrix” that is cartilage. These calls can die off and calcify when they don’t receive nutrients or waste diffusion is blocked. Because it does not have its own blood supply, cartilage must be “maintained” by the motion of the joint to move nutrients in and out. The cartilage and bones are surrounded by synovial fluid, which is essentially a lubricant. Arthritis weakens the cartilage and causes the breakdown of synovial fluid by slowing or halting the exchange of nutrients in the cartilage matrix. This causes inflammation and eventually, the cartilage will be worn away.

Just like humans, dogs need to stay active for both mental and physical health. It can be extremely depressing for a once active dog to experience joint pain and some dogs will continue to run, jump, and play, even when it hurts because they just don’t understand they shouldn’t. This puts them at high risk for added injury or additional health problems aggravated by chronic pain or decreased mobility, such as a dog harming himself because he is no longer able to jump onto a bed or over a hurdle. Inactivity is also dangerous for dogs who slow down too much due to pain and the snowball effect is that their muscles, joints and bodies atrophy.

Osteoarthritis is not the only culprit that can break down your dog’s cartilage but it is one of the most frequently diagnosed health problems in mature dogs.

Some dogs such as performance, hunting or service animals experience higher levels of strain on their joints. Some breeds are just more susceptible to joint issues through heredity or poor breeding- consider the rampant hip dysplasia in German shepherds. Degenerative diseases and inflammation in your dog’s body can also break down cartilage. It’s important to stay vigilant and pay close attention to your dog’s health but also to take a preventative approach. If your dog has had surgeries or regularly performs at a high level of activity you will want to keep a close on eye on his joint health. Common areas of injury or pain include their hips, back, knees, shoulders, and elbows. Even something as simple as the wrong kind of food or an allergy can cause inflammation in your dog that will manifest itself in the weakest points of his body.

Dog joint supplements can help relieve joint pain but also increase mobility, assist in recovery from injuries or trauma, and help your dog maintain a level of activity that will maintain his muscular and skeletal system. Some veterinarians even recommend beginning joint therapy supplements before the problem begins in some breeds and professions, and some dogs begin taking these supplements as soon as they reach adulthood. It is a decision you should make with the help of a medical professional. Before starting glucosamine supplement therapy be sure your vet has thoroughly examined your dog to ensure there are no other health concerns that could be causing his joint pain or stiffness. A diagnosis of arthritis can be tough but you may be surprised at how easy it is to alleviate. Many dogs respond well to glucosamine therapy.

Glucosamine is an amino sugar that occurs naturally in the cartilage matrix but for supplements, is typically derived from shellfish. It can also be synthesized from plant-based material. The most commonly used glucosamine in pet supplements used is glucosamine sulfate. The sulfur in this substance is the component that is believed to help stimulate cartilage. Glucosamine hydrochloride is less effective but does not contain sulfates. And finally, there is N-acetyl-glucosamine which is a derivative of glucose. Some products contain chitosan, which is an altered form of N-acetyl-glucosamine. It’s not going to be as effective as glucosamine sulfate but is reported to help with gastrointestinal and immune system issues.

It is thought that chondrocytes within the cartilage matrix are stimulated by glucosamine. Studies have shown both an anti-inflammatory response helps relieve pain and protects against further degradation of the joint structure.

While your dog may respond well to pain medications that also have an anti-inflammatory effect, the side effects of long term use of non-steroidal anti-inflammatory drugs (NSAIDS) on dogs is something to consider. Common side effects include irreversible damage to their urinary and digestive systems.

Glucosamine does not have nearly as long a list of potential negative side-effects but because it is a sugar-based substance you should be careful about using it with dogs who already have diabetes.

All supplements are not made equal. Unfortunately, the pet supplement market is not well-regulated as these are not considered drugs. Consequentially, there are a lot of snake oil grade products out there manufactured by questionable companies using even more questionable ingredients. Dog food is not the only thing that may be made in facilities that do not care about the health of your animal.

It is critical to read your ingredients and understand what’s in the supplements before you give them to your four-legged family member. Many of them are harmless and just contain filler material or are basically an overpriced, overhyped dog treat with trace amounts of vitamins or other ”healthy” substances, but some contain ingredients that could make your dog sick or at the very least put him at a higher risk for health problems down the road. Many supplements are loaded with sweeteners and sugars, preservatives and fillers such as soy, that is difficult for your dog to digest. Some major ones to avoid are propylene glycol (PG), BHA (butylated hydroxyanisole), BHT (butylated hydroxytoluene), ethoxyquin, and food dyes such as Blue 2, Red 40. The supplement should have all ingredients and quantities clearly labeled.

A good supplement will pair glucosamine sulfate or glucosamine hydrochloride (HCl) with other nutrients and substances to maximize the effectiveness for your dog. Glucosamine is commonly paired with chondroitin, which helps retain water in the joint area. Methylsulfonylmethane (MSM) is also a great ingredient for reducing inflammation. Some supplements also include vitamins, minerals, and other substances to enhance the supplement. Hyaluronic acid is good for the synovial fluid around joints and elsewhere in the body. Turmeric is also growing in popularity for pet supplements due to its strong anti-inflammatory and antioxidant properties.

While glucosamine supplements come in multiple forms, consider how easy it will be for your dog to digest and his body to absorb what’s in the supplement. Does he easily take pills or would you struggle to get him to take several pills or chewable tablets a day? Some older dogs are on soft or wet food only and it may be difficult for them to take a chewable that’s hard to chew.

Most glucosamine supplements come in one of the following forms:

Chewable style:  A soft or hard chewable tablet that you can give the dog directly without pill pockets or having to hide in his food

  • Usually meat flavored like a treat
  • More expensive as dog will need to take more of them for appropriate dosage
  • Some chewables may be too hard for dogs needing a soft texture

Pill style:  A pill taken orally with higher concentrations of the compounds

  • Not all dogs easily take pills

Powder style:  Powdered form that can be added to pet’s food or treats

  • May make dog reluctant to eat their food if they don’t like the flavor
  • May not blend well with dog’s food or water
  • May have bitter or unpleasant taste

Liquid style:  Liquid that may be added to dog’s food or water

  • May not absorb as slowly as other forms and can cause adverse reaction
  • Some dogs will not drink water or eat food with added supplements
  • May not blend well

Finding a supplement that is right for your dog may take time and trial-and-error. Always pay close attention to your dog when making any changes in his diet, adding supplements or other medications and be sure there are no potential interactions or adverse effects.